Scutellaria baicalensis is another of the 50 fundamental herbal medicine used in China. Its use was first recorded in “Shen Nong’s herbal classic” (200-300 A.D.).

It is widely used as both a dietary ingredient and as a herbal medicine to treat inflammatory diseases, allergy, and bacterial and viral infections. According to Chinese Pharmacopoeia, Huang Qin is an ingredient in more than 170 herbal formulas

The pharmacological properties of S. baicalensis components include anti-inflammatory, antitumor, neuroprotective, cardiovascular protective, hepatoprotective, antiallergic, anticancer, antiviral and antibacterial activities.

‍S. baicalensis root is rich in glycoflavones, primarily baicalin, baicalein and wogonoside, both of which appear alongside smaller amounts of their aglycones. Oroxylin A is also present, liquiritigenin and isoliquiritigenin. The components are associated with a variety of pharmacological actions, including antimicrobial, antiallergic, anti-inflammatory, antioxidative, diuretic, cholagogic, choleretic, spasmolytic, antihypertensive, and antipyretic actions, as well as effects on the central nervous system and lipid metabolism. In the skin, S. baicalensis root extract was found to promote keratinocyte differentiation and to help restore skin barrier function.